Claudin 1 抗体 (Middle Region)
Quick Overview for Claudin 1 抗体 (Middle Region) (ABIN7603005)
抗原
See all Claudin 1 (CLDN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Anti-Claudin 1/CLDN1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins.
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产品特性
- Anti-Claudin 1/CLDN1 Antibody (ABIN7603005). Tested in IF, IHC, ICC applications. This antibody reacts with Human.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence in the middle region of human Claudin 1/CLDN1, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-Claudin 1 (CLDN1) (AA 1-211) antibody
CLDN1 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1C5-D9 unconjugated
anti-Claudin 1 (CLDN1) (AA 1-211) antibodyCLDN1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 2E2-H5 unconjugated
anti-Claudin 1 (CLDN1) (AA 121-211) antibodyCLDN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 50-197) antibodyCLDN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (C-Term) antibodyCLDN1 适用: 人, 大鼠, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 1-212) antibodyCLDN1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C5-D9 unconjugated
anti-Claudin 1 (CLDN1) (Tyr210) antibodyCLDN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 24-161) antibodyCLDN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (C-Term) antibodyCLDN1 适用: 人, 犬, Cow, 绵羊, 猴, 豚鼠, 马, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 1-211) antibodyCLDN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
1. Baala, L., Hadj-Rabia, S., Hamel-Teillac, D., Hadchouel, M., Prost, C., Leal, S. M., Jacquemin, E., Sefiani, A., de Prost, Y., Courtois, G., Munnich, A., Lyonnet, S., Vabres, P. Homozygosity mapping of a locus for a novel syndromic ichthyosis to chromosome 3q27-q28. J. Invest. Derm. 119: 70-76, 2002. 2. Coyne, C. B., Gambling, T. M., Boucher, R. C., Carson, J. L., Johnson, L. G. Role of claudin interactions in airway tight junctional permeability. Am. J. Physiol. Lung Cell. Molec. Physiol. 285: L1166-L1178, 2003. 3. Dhawan, P., Singh, A. B., Deane, N. G., No, Y., Shiou, S.-R., Schmidt, C., Neff, J., Washington, M. K., Beauchamp, R. D. Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer. J. Clin. Invest. 115: 1765-1776, 2005. -
限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- Claudin 1 (CLDN1)
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别名
- CLDN1
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背景
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Synonyms: Growth/differentiation factor 15,GDF-15,Macrophage inhibitory cytokine 1,MIC-1,NSAID-activated gene 1 protein,NAG-1,NSAID-regulated gene 1 protein,NRG-1,Placental TGF-beta,Placental bone morphogenetic protein,Prostate differentiation factor,GDF15,MIC1, PDF, PLAB, PTGFB,
Tissue Specificity: Highly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
Background: Claudin-1 is a protein that in humans is encoded by the CLDN1 gene. Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome.
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分子量
- 34 kDa
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基因ID
- 9076
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UniProt
- O95832
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途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
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